Serum levels of caffeine in umbilical cord and apnea of prematurity

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Serum levels of caffeine in umbilical cord and apnea of prematurity.

OBJECTIVE To determine the influence of presence of caffeine in umbilical cord blood on apnea occurrence. METHODS A prospective cohort study with preterm newborns with birth weight lower than 2,000 g was undertaken. Exclusion criteria were: mothers who received opioids; mechanical ventilation during the first 4 days of life; cerebral and major cardiac malformations; perinatal asphyxia; severe...

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Effect of Caffeine and Aminophylline on Apnea of Prematurity

Background: The most common type of apnea among premature newborns is idiopathic apnea of prematurity. Recurrent apnea can lead to hypoxemia and central nervous system damage. Although caffeine and theophylline are the most commonly prescribed drugs in this field, there is disagreement about which medicine is preferred. The purpose of this study was to compare the ther...

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: the effect of sericin levels (silk glue protein) on rate of in vitro maturation, fertilization and culture of sheep oocytes

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Caffeine therapy for apnea of prematurity.

BACKGROUND Methylxanthines reduce the frequency of apnea of prematurity and the need for mechanical ventilation during the first seven days of therapy. It is uncertain whether methylxanthines have other short- and long-term benefits or risks in infants with very low birth weight. METHODS We randomly assigned 2006 infants with birth weights of 500 to 1250 g during the first 10 days of life to ...

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Comparison between Caffeine and Theophylline Therapy for Apnea of Prematurity

Purpose: Methylxanthines are commonly used to treat apnea of prematurity. Recent studies have reported that caffeine therapy reduces the rate of bronchopulmonary dysplasia (BPD) and improves the rate of survival in preterm infant without neuro­ developmental disabilities. This study was performed to compare the effects on apnea episodes, adverse effects and morbidity between the caffeine and th...

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ژورنال

عنوان ژورنال: Jornal de Pediatria

سال: 2010

ISSN: 0021-7557

DOI: 10.2223/jped.1990